Susan trained at Tufts and studied kidney disease and pregnancy. Her work helped physicians understand how to care for women with kidney disease who wanted to have children. She also co-authored research on living kidney donation.

In 1996, Susan helped arrange a living-donor liver transplant for Indira, a five-year-old girl from Bolivia. She and her husband, Mark Molitch, spent years traveling to Bolivia and working with Douglas Villarroel. On September 14, 2001, the three physicians co-founded the clinic in Palacios.

In 2002, Susan donated a kidney to a patient she was not related to. Six colleagues at Loyola later became donors as well. They became known as the “Seven Sisters” of organ donation.

On October 10, 2014, exactly twelve years after donating a kidney, Susan received a lung transplant. She had been diagnosed with pulmonary fibrosis in 2010. When her transplant medicines later damaged her kidney, her son Ethan donated one of his to her in 2017.

Susan died in 2019 at age 72. The clinic was later renamed Centro Médico Susan Hou in her honor.